The Minnesota Opioid Prescribing Guidelines will help Minnesota communities reduce opioid prescriptions; encourage safe, consistent standards when opioids are called for, and deliver compassionate support to people who need ongoing opioid therapy. Built on the understanding that opioids are not the best option for treating chronic pain and may actually worsen it, Minnesota's guidelines focus on post-acute care - the first 45 days after an injury.

The Opioid Prescribing Work Group was convened through 2019 to advance the program's work, which includes developing statewide guidelines on appropriate opioid prescribing. The opioid prescribing guidelines are a joing effort of the medical community and the Minnesota Department of Health and Department of Human Services.