Drug - Pristiq (desvenlafaxine)
Therapeutic area - major depressive disorder
Available as 50 mg and 100 mg tablets
One of either strength allowed per day
The recommended dose is 50 mg once daily. No additional benefit has been seen at doses higher than 50mg, while adverse events and discontinuations were more frequent at higher doses.
Paroxetine (Paxil, Paxil CR)
Desvenlafaxine is a metabolite of venlafaxine. Venlafaxine and desvenlafaxine are considered pharmacologically approximately equiactive and equipotent. The drug-drug interaction profile is similar between venlafaxine and desvenlafaxine.
MHCP Provider Call Center 651-431-2700 or 800-366-5411